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Hormones come in a variety of forms. Some hormones are lipid-soluble; others are water-soluble. Which of the following statements accurately describe water-soluble hormones?A. receptors are located on the membranes of target cellsB. binding to receptors on target cells often triggers signal transduction pathwaysC. usually directly affect gene expression by acting as transcription factorsD. Both A & BE. Both B & C

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