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Ex. water deprivation water is lost and not replaced while solutes (salts) are conserved,The concentrated salts result in increased ECF osmolarity since salts were not lostResulting in a FLUID shift - Water moves from ICF to ECF which is hypertonic to reach equilibrium (usually not enough to compensate)Possible hypotension can develop, hypernatremia, damage to shrinking cells.Replace with hypotonic solution

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