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You suspect that a serious developmental disorder is due to a chromosome abnormality and prepare a karyotype from an affected individual. In analyzing the karyotype, how could you distinguish trisomy from a chromosome structural defect such as a duplication? a) The chromosome number in both cases would be normal, but in trisomy there would be three chromatids on one chromosome and in a duplication there would be two chromatids on one chromosome. B) The chromosome number in trisomy would be normal; in a duplication, there would be one more chromosome. C) In both cases there would be an extra chromosome, but in trisomy there would be three chromatids on one chromosome and in a duplication there would be two chromatids on one chromosome. D) In trisomy there would be one extra chromosome; in a duplication, the number of chromosomes would be normal, but one chromosome would have two copies of a portion of the chromosome.

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