Medicine Questions
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Cationic drugs and weak bases are more likely to bind to:a. Albuminb. Lipoproteinsc. Alpha-1-acid glycoproteind. Erythrocytes
Refers to the highest concentration in the plasma concentration-time profilea. Cmaxb. Tmaxc. AUC
Phospholipids have a a. Hydrophilic Head & Hydrophilic Tailb. Hydrophobic Head & Hydrophobic Tailc. Hydrophilic Head & Hydrophobic Taild. Hydrophobic Head & Hydrophilic Tail
Characteristics of enterohepatic cycling of drug metabolites include the following:a. Plasma concentration-time profile shows a second peakb. Excretion into bile requires high lipophilicityc. Only low molecular weight metabolites (less than 300) are excreted into the biled. Concurrent antibiotic administration increases the enterohepatic cycling of drugs that form glucuronides
Which of the following is a phase 2 metabolic pathway?a. Oxidationb. Reductionc. Hydrolysisd. Glucuronidation
The liver extraction ratio of four drugs is given below. Which of these drugs would have the highest oral bioavailability?a. Nitroglycerin, 0.9b. Propranolol, 0.6c. Pentazocine, 0.8d. Lidocaine, 0.7
Anionic drugs and weak acids are more likely to bind to:a. Albuminb. Lipoproteinsc. Alpha-1-acid glycoproteind. Erythrocytes
____________ controls cortisol levels. Without it, Cortisol levels will excessively increase.
The "abortion pill" is a class of _____________ that inhibits Progesterone. Progesterone is a hormone that maintains pregnancy.
Renin is produced by ______________ cells in the kidney.
____________ is the counter-hormone of Insulin and is secreted in response to Hypoglycemia.
_______ and ________ are 2 hormones that secreted by the kidney.
Type ___ Diabetes is an autoimmune disease that may be triggered by a viral infection.
Renin is primarily composed of 406 _________ ______.
Aldosterone and Cortisol have a _____ ratio.
Too much or too little use of Glucocorticoids will __________ susceptibility of infection.
Alternatively to Insulin, Glucagon utilizes the ______ system to increase blood glucose.
What actions (4) does Metformin do to decrease glucose absorption from the gut to help control diabetes?
Renin stimulates the production of ____________ to re-establish blood pressure + stimulate release of ______________ from the Adrenal Gland.
Hyperglycemia (high blood glucose levels) stimulates _______ cells to produce __________.