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translocation cotraductionnelle-le peptide signal est --- pendant la translocation-la séquence --- --- est structuré en --- hélices, et empeche la migration de la protéine vers l'intérieur du --- ----le ribosome est donc --- de la membrane-l'absence de peptide signal est parfois remplacé par la séquence du premier domaine --- (=transmembranaire), qui va s'accrocher au recepteur de la sequence signal mais elle ne sera pas --- -> --- de l'orientation = type ---, ou pas = type ----si la protéine à plusieurs domaines tm, une premiere --- --- = signal d'adressage à la membrane et une deuxieme signal contient l'information nécessaire pour --- la translocation

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