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On prépare une solution composée de 500 mL d'eau distillée et 500 mL de sérum salé isotonique. On l'injecte à un nouveau-né de 5kg, dont les volumes liquidiens sont ceux attendus physiologiquement en moyenne. En fin de perfusion, après équilibration entre les secteurs intra- et extracellulaire mais avant toute régulation rénale :Une mesure du volume du liquide intracellulaire à l'aide d'un traceur donnerait un résultat de 1.2 L

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