Hematology Questions
Explore questions in the Hematology category that you can ask Spark.E!
Hb abnormalities, mismatched blood, bacterial or parasytical infections (malaria)
A common stem cell (pluripotent= can be any blood cell)
Sickle cell disease carrier has Hgb
The main stimulus for RBC production is
Proteins that elicit immune response and identifies the cell
Binds to albumin in plasma, and goes to the liver => Goes into Bile and gets secreted
"Committment" occurs when the cell has receptors that bind to Hematopoietic Growth Factors
1) Hypoxia2) Low blood Osmolarity3) Low blood Viscosity
1) Nutrition deficiency (iron, B12, Folic acid - B9)2) Pernicious anemia (no intrinsic factor, no gastric secretion)3) Renal anemia (no EPO)4) Aplastic anemia (destruction of red marrow via drugs/radiation)
1) Hemorrhagic2) Low Hgb Synthesis (4 subcategories)3) Hemolytic anemia
They die after 120 days, and should go to the Spleen.But can get stuck in vessels also
Sickles red cells cause anemia because they have a decreased
4-6 million per mm^3 (as shown on a RBC count in a CBC)
Each Hgb contains _ heme groups; meaning 1 Hgb can carry up to _ oxygens
Hgb S is a result of minor changes in the molecular structure causing profound changes in
% of whole blood volume that is composed of RBC's
Because RBCs do not undergo mitotic division, they are replaced by
Folic Acid Anemia is different from Vitamin B12 anemia by lack of
Hypoxia is sensed by the kidneys, which the produces the hormone
When all 4 heme groups are bonded with oxygen, it is said to be