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One way to help their efficiency is to REDUCE the amount of energy it takes for exergonic reactions to take place, so use enzymes...... are biological catalysts that lower the amount of activation energy (initial energy investment) needed to start a reaction. Enzymes always end in -...., are proteins.They often have really ... 3-dimensional shapes. Theses shapes are most perfect for holding other molecules in very specific sites called active sites. By holding other molecules in place, we can lower the activation energy needed to get a spontaneous reaction to begin.

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