Biophysics Questions
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NERNST EQUATION: Concentration gradient ≈ electrical gradient: If that ion is Na+: Vm = Vrest = VNa+ =
•Regulated ion channels: Ligand-gated channel: which type of Ligands ? (3)
MOVEMENT OF IONS ACROSS THE MEMBRANE:The electrical gradient:▪ Attracts K+ towards the ... ofthe cell.▪ Attracts Na+ towards the... compartment.
Whats the other name for the Non-regulated ion channels
MEMBRANE POTENTIALRESTING MEMBRANE POTENTIAL in NEURONS CAN CHANGE = EXCITABLE cellsTYPICAL RESTING POTENTIAL of a NEURON =
Electrical gradient + Chemical (concentration)gradient
The resting membrane potential depends on two factors that influence the magnitude and direction of Na+ and K+ diffusion across the plasma membrane. Identify these two factors.
Suppose a drug is developed that blocks K+ leakage channels. The drug prevents ions from passing through those channels. If this drug was applied to a neuron, what would be the most immediate effect on that neuron?
Ions are unequally distributed across the plasma membrane of all cells. This ion distribution creates an electrical potential difference across the membrane. What is the name given to this potential difference?
The channels that provide for the movement of potassium in the resting neuron are__________.
Establishing the resting membrane potential requires energy through the use of the _______.
Imagine you changed the concentration of K+ outside a neuron such that the resting membrane potential changed to -80 mV (from the normal resting value of -70 mV). What have you changed?
What prevents the Na+ and K+ gradients from dissipating?
Which of the following would increase the membrane permeability to K+?
What effect did increasing the extra cellular potassium have on the resting membrane potential?
Hypothetically, what would be the most immediate effect of doubting the number of Na+ leakage channels in the plasma membrane?
Sodium and potassium ions can diffuse across the plasma membranes of all cells because of the presence of what type of channel?
Which of the following is the clearest example of the neuronal membrane's selective permeability?
A molecule that carries information across a synaptic cleft is a
When neurotransmitter molecules bind to receptors in the plasma membrane of the receiving neuron,