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Biochemistry Questions

Explore questions in the Biochemistry category that you can ask Spark.E!

Bisphosphonates act as inhibitors of which step(s) in cholesterol biosynthesis? A. Formation of geranyl PP from isopentenyl-5-pyrophosphate B. Formation of mevalonic acid from 3-hydroxy-3-methylglutaryl CoA C. Formation of farnesyl PP from isopentenyl-5-pyrophosphate D. Formation of isopentenyl-5-pyrophosphate from mevalonate-5-pyrophosphate

Which enzyme controls the committed step in cholesterol biosynthesis? A. HMG CoA reductase B. Fatty acid synthetase C. Acetyl CoA carboxylase D. Carnitine acyl transferase

The physiologically active form of vitamin D produced in the kidney is: A. 7-dehydrocholesterol B. 1,25-dihydroxycholecalciferol C. 25-hydroxycholecalciferol D. Cholecalciferol

Which compound is produced in both the gonads and the adrenal cortex? A. cholesterol B. progesterone C. testosterone D. estradiol

Why are essential fatty acids (EFAs) important in our diet? A. EFAs cannot be made by our bodies but are needed to produce other important molecules B. EFAs are used as a primary source of long term energy storage C. EFAs contribute to B vitamin synthesis D. All of the above

Which of the following phospholipid headgroups has a positive charge? (select all that apply) A. Phosphatidylinositol B. Phosphatidylserine C. Sphingomyelin D. Phosphatidylcholine

Which lipoprotein complexes are associated with the overflow pathway of cholesterol transport? A. LDL, HDL and chylomicrons B. LDL and chylomicrons C. IDD, LDL and VLDL D. LDL and HDL

Fatty acid synthesis occurs in which part of the cell A. the mitochondrion B. the cytoplasm C. the nucleus D. the membrane E. the endoplasmic reticulum

Cerebrosides are phospholipidsA. TrueB. False

Which of the following phospholipid headgroups contributes no charge? (select all that apply) A. Phosphatidylcholine B. Phosphatidylserine C. Phosphatidylinositol D. Phosphatidic acid

Cholesterol consists of four fused rings and (select all that apply) A. a hydroxyl group B. a hydrocarbon tail C. a ketone group D. an aldose group

What properties allow lipid assembly into a membrane bilayer? A. hydrophobic headgroup / hydrophobic FA tail B. polar headgroup / polar FA tail C. hydrophobic headgroup / polar FA tail D. polar headgroup / hydrophobic FA tail

Which steps are irreversible in glycolysis?

Which statement about beta-oxidation and synthesis of fatty acids is NOT correct? A. Both synthesis and beta-oxidation occur in steps of 2 carbon fragments. B. Breakdown of fatty acids creates NADH that can feed into the electron transport chain. C. Beta-oxidation involves a number of reduction reactions. D. Beta-oxidation is simply the direct reversal of all the same steps that occur in synthesis.

Which of the following fatty acids requires an additional set of enzymes for oxidation by the mitochondria? A. odd-chain B. unsaturated C. polyunsaturated D. All the above

Sphingosine forms an amide bond with the fatty acid chainA. TrueB. False

HMG CoA reductase is inhibited by (select all that apply) A. phosphatase B. kinase C. glucagon D. insulin

Oxidation of fatty acids occurs in the A. mitochondrial matrix B. outer mitochondrial membranes C. cytosol D. intermembrane space E. Golgi apparatus

Which organ is responsible for the final processing step in Vitamin 1,25-D synthesis? A. Kidney B. Gonads C. Adrenal gland D. Liver

What bile salt acts as precursor for other bile salts? A. taurocholic acid B. glycocholic acid C. cholic acid D. deoxycholic acid

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